BK Virus Infection in Renal Allograft Recipients
نویسنده
چکیده
BK virus infection is a challenging complication in renal allograft recipients and has been associated with hematuria, ureteral stenosis, nephropathy and malignancy. BK virus infection occurs early during childhood and the virus lays dormant in uroepithelial cells. Reactivation of the virus in renal transplant recipients is particularly worrisome because of its propensity to cause local damage and incite an inflammatory response leading to acute kidney injury and possible graft loss. Recent, OPTN (Organ Procurement and Transplant Network) registry analysis suggests that the incidence of BK virus related complications are rising and between June 2004 and December 2008, 823 grafts were lost secondary to BK virus related complications [1]. This review will focus on BKV nephropathy (BKVN) in renal allograft recipients.
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بررسی مولکولی فعالیت مجدد ویروس BK در ادرار بیماران پیوند کلیه
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